β-Cortol

CAS : 667-65-2

Ref. TR-C696295

Informations sur le produit

• Nom: β-Cortol
• Synonymes: Pregnane-3,11,17,20,21-pentol, (3α,5β,11β,20R)-, 5β-Pregnane-3α,11β,17,20β,21-pentol (7CI,8CI), (3α,5β,11β,20R)-Pregnane-3,11,17,20,21-pentol, 20β-Cortol, 3α,11β,17,20β,21-Pentahydroxypregnane, 5β-Pregnan-3α,11β,20,20β,21-pentol, 5β-Pregnane-3α,11β,17α,20β,21-pentol, Cortol-20β, NSC 58792, Pregnane-3α,11β,17,20β,21-pentol
• Marque: TRC
• Description: Stability HygroscopicApplications β-Cortol is a metabolite of cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.References Pasqualini, J.R., et. al.: J. Eur. Steroids, 1, 63 (1966); Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol., 296 (2009)

Propriétés chimiques

• Masse moléculaire: 368.5
• Formule: C₂₁H₃₆O₅
• Couleur/Forme: Neat
• InChI: InChI=1S/C21H36O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12-18,22-26H,3-11H2,1-2H3/t12-,13-,14+,15+,16+,17-,18-,19+,20+,21+/m1/s1
• Code InChI: InChIKey=FFPUNPBUZDTHJI-ZFOKFBPFSA-N
• SMILES: C[C@]12CC[C@@H](O)C[C@H]1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)[C@H](O)CO