CX 546

CAS : 215923-54-9

Ref. TR-C858000

Informations sur le produit

• Nom: CX 546
• Synonymes: 2,3-dihydro-1,4-benzodioxin-6-yl(piperidin-1-yl)methanone, (2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylmethanone, 1-(1,4-Benzodioxan-6-ylcarbonyl)piperidine, 1-(2,3-Dihydro-1,4-benzodioxin-6-ylcarbonyl)piperidine, 1-(2,3-Dihydro-1,4-benzodioxine-6-carbonyl)piperidine, 2,3-Dihydro-1,4-Benzodioxin-6-Yl(Piperidin-1-Yl)Methanone, Bdp 17, Gr 87, Methanone, (2,3-dihydro-1,4-benzodioxin-6-yl)-1-piperidinyl-, Piperidine, 1-[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]-

Description

Applications It is one of a series of AMPA modulators for the potential treatment of Alzheimer's disease, schizophrenia, and mild cognitive impairment (MCI). An ampakine drug that facilitates activation of glutamatergic AMPA receptors.
References Partin, K., et al.: J. Neurosci.,16, 6634 (1996), Vanover, K., et al.: Eur. J. Pharmacol., 332, 115 (1997), Moser, P., et al.: Brain Res. Rev., 33, 275 (2000), Kinney, G., et al.: J. Pharmacol. Exp. Ther., 306, 116 (2003),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 247.29
• Formule: C₁₄H₁₇NO₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C14H17NO3/c16-14(15-6-2-1-3-7-15)11-4-5-12-13(10-11)18-9-8-17-12/h4-5,10H,1-3,6-9H2
• Code InChI: InChIKey=LJUNPHMOGNFFOS-UHFFFAOYSA-N
• SMILES: O=C(c1ccc2c(c1)OCCO2)N1CCCCC1