(4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester
CAS : 125971-94-0
Ref. TR-C982020
10g | 1.569,00 € | ||
500mg | 194,00 € | ||
2500mg | 541,00 € |
Informations sur le produit
- 1,3-Dioxane-4-acetic acid
- 6-(cyanomethyl)-2,2-dimethyl-
- 1,1-dimethylethyl ester
- (4R,6R)-
- : 1,3-Dioxane-4-acetic acid
- 6-(cyanomethyl)-2,2-dimethyl-
- 1,1-dimethylethyl ester
- (4R-cis)-
- ((4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-[1,3]dioxan-4-yl)acetic acid tert-butyl ester
- (6R-Cyanomethyl-2,2-dimethyl-[1,3]dioxan-4R-yl)acetic acid tert-butyl ester
- Voir d'autres synonymes
- (4R,3R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
- (4R,6R)-Tert-Butyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate
- (4R,6R)-t-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
- (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate (ATS-8)
- (4R,Cis)-1,1-dimethylethyl-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
- (4R-cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
- (4R-cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2-dlmethyl-1,3-dioxane-4-acetate
- 1,1-Dimethylethyl (4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
- 1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)-
- 1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R-cis)-
- ATS-8(for Atorvastatin)
- Ast-8
- Atorvastatin Calcium Intermediate ATS-8
- AtorvastatinCalcium(ATS-8)
- Ats-8
- Tert-Butyl (4R,3R)-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate
- Tert-Butyl 2-((4R,6R)-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl) acetate
- tert-Butyl(3R,5R)-6-cyano-3,5-O-iso-propylidene-3,5-dihydroxyhexanoate
- tert-butyl [(4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate
Applications (4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester is an intermediate of Atorvastatin (A791750, Ca salt), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000),
Propriétés chimiques
Question d’ordre technique sur : TR-C982020 (4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester
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