[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN') Diiodoplatinum

CAS : 66845-32-7

Ref. TR-C984525

Informations sur le produit

• Nom: [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN') Diiodoplatinum
• Synonymes: (trans-1R,2R-1,2-Diaminocyclohexane)diiodoplatinum, (trans-R,R-1,2-Diaminocyclohexane)diiodoplatinum, (trans-R,R-Cyclohexane-1,2-diamine)diiodoplatinum, Diiodo(trans-l-1,2-cyclohexanediamine)platinum, NSC 290127,(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN,κN']diiodoplatinum, (1R-trans)-1,2-Cyclohexanediamine Platinum Complex, [SP-4-2-(1R-trans)]-(1,2-cyclohexanediamine-N,N')diiodoplatinum, USP Oxaliplatin Related Compound
• Marque: TRC
• Description: Applications [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN')diiodoplatinum is a potential antitumor agent. Impurity of Oxiplatin (O845075), third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.References Kidani, Y. et al.: Biomed. Pharmacther., 43, 261 (1989); Noji, M. et al.: J. Med. Chem., 24, 508 (1981); Kidani, Y., et al.: J. Med. Chem., 21, 1315 (1978), Kizu, R., et al.: Cancer Chemother. Pharmacol., 31, 475 (1993), Levi, F., et al.: Eur. J. Cancer, 29A, 1280 (1993), Simpson, D., et al.: Drugs, 63, 2127 (2003),

Propriétés chimiques

• Masse moléculaire: 563.08
• Formule: C₆H₁₄I₂N₂Pt
• Couleur/Forme: Neat
• InChI: InChI=1S/C6H14N2.2HI.Pt/c7-5-3-1-2-4-6(5)8;;;/h5-6H,1-4,7-8H2;2*1H;/q;;;+2/p-2/t5-,6-;;;/m1.../s1
• Code InChI: InChIKey=AEAVNKNQJBFMCW-SKSSAGQDSA-L