8-Cyclopentyl-1,3-dipropylxanthine

CAS : 102146-07-6

Ref. TR-C988500

Informations sur le produit

• Nom: 8-Cyclopentyl-1,3-dipropylxanthine
• Synonymes: 8-cyclopentyl-1,3-dipropyl-7H-purine-2,6-dione, 1,3-Dipropyl-8-cyclopentylxanthine, 1,3-Dpcpx, 1H-Purine-2,6-dione, 8-cyclopentyl-3,7-dihydro-1,3-dipropyl-, 1H-Purine-2,6-dione, 8-cyclopentyl-3,9-dihydro-1,3-dipropyl-, 8-Cyclopentyl-3,7-dihydro-1,3-dipropyl-1H-purin-2,6-dione, 8-Cyclopentyl-3,9-dihydro-1,3-dipropyl-1H-purine-2,6-dione, 8-cyclopentyl-1,3-dipropyl-3,7-dihydro-1H-purine-2,6-dione, Dpcpx, Pd 116948, 8-Cyclopentyl-1,3-dipropylxanthine

Description

Applications DPCPX is a potent and very selective A1-adenosine receptor antagonist, with a Ki of 0.46 nM for A1 receptors in rat whole-brain membranes. Its 740-fold A1-selectivity is the highest reported for an adenosine antagonist.
References Gessi, S., et al.: Mol. Pharmacol., 67, 2137 (2005), Minor, T.R., et al.: Behav. Neurosci., 122, 1236 (2008), Gracia, E., et al.: J. Neurochem., 107, 161 (2008), Gessi, S., et al.: Biochem. Pharmacol., 75, 562 (2008),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 304.39
• Formule: C₁₆H₂₄N₄O₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C16H24N4O2/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18)
• Code InChI: InChIKey=FFBDFADSZUINTG-UHFFFAOYSA-N
• SMILES: CCCn1c(=O)c2[nH]c(C3CCCC3)nc2n(CCC)c1=O