Cyproterone

CAS : 2098-66-0

Ref. TR-C989090

Informations sur le produit

• Nom: Cyproterone
• Synonymes: 3'H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1,2-dihydro-17-hydroxy-, (1beta,2beta)-, 3'H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1beta,2beta-dihydro-17-hydroxy- (8CI), Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-1alpha,2alpha-methylene- (7CI), (1beta,2beta)-6-Chloro-1,2-dihydro-17-hydroxy-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 1,2alpha-Methylene-6-chloro-6-17alpha-hydroxyprogesterone, 6-Chloro-1,2alpha-methylene-4,6-pregnadien-17alpha-ol-3,20-dione, 6-Chloro-17-hydroxy-1alpha,2alpha-methylenepregna-4,6-diene-3,20-dione, 6-Chloro-6-dehydro-17alpha-hydroxy-1,2alpha-methyleneprogesterone, SH 80881, SH 881, (1R,3aS,3bR,7aR,8aS,8bS,8cS,10aS)-1-acetyl-5-chloro-1-hydroxy-8b,10a-dimethyl-2,3,3a,3b,7a,8,8a,8b,8c,9,10,10a-dodecahydrocyclopenta[a]cyclopropa[g]phenanthren-7(1H)-one, (1R,7aR,8aS)-1-acetyl-5-chloro-1-hydroxy-8b,10a-dimethyl-2,3,3a,3b,7a,8,8a,8b,8c,9,10,10a-dodecahydrocyclopenta[a]cyclopropa[g]phenanthren-7(1H)-one, (1R,7aR,8bS,10aS)-1-acetyl-5-chloro-1-hydroxy-8b,10a-dimethyl-2,3,3a,3b,7a,8,8a,8b,8c,9,10,10a-dodecahydrocyclopenta[a]cyclopropa[g]phenanthren-7(1H)-one, (1β,2β)-6-Chloro-1,2-dihydro-17-hydroxy-3′H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 1,2α-Methylene-6-chloro-⁶-17α-hydroxyprogesterone, 3'H-Cyclopropa(1,2)pregna-1,4,6-triene-3,20-dione, 6-chloro-1-beta,2-beta-dihydro-17-hydroxy-, 3′H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1,2-dihydro-17-hydroxy-, (1β,2β)-, 3′H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1β,2β-dihydro-17-hydroxy-, 6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteron, 6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteron [German], 6-Chloro-1,2α-methylene-4,6-pregnadien-17α-ol-3,20-dione, 6-Chloro-17-hydroxy-1α,2α-methylenepregna-4,6-diene-3,20-dione, 6-Chloro-6-dehydro-17α-hydroxy-1,2α-methyleneprogesterone, Bay 94-8367, Bay94-8367, Ciproterona, Ciproterona [INN-Spanish], Ciproterone, Ciproterone [DCIT], Cyproteron, Cyproterone [INN:BAN], Cyproteronum, Cyproteronum [INN-Latin], Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-1α,2α-methylene-, Sh 80881, Sh 881, Unii-E61Q31Ek2F

Description

Impurity Cyproterone Acetate EP Impurity F
Applications Cyproterone (Cyproterone Acetate EP Impurity F) is an antiandrogen, suppresses Testosterone and its metabolites. Derivatives of Cyproterone are administered to patients suffering from hypersexuality and to help facilitate the sexual transformation of male-to-female transsexuals.
References Gracia, T., et al.: Toxicol. App. Pharmacol., 225, 142 (2007), Ahlin, G., et al.: J. Med. Chem., 51, 5932 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Bovee, T., et al.: J. Steroid Biochem. Mol. Biol., 118, 85 (2010),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 374.90
• Formule: C₂₂H₂₇ClO₃
• Couleur/Forme: Off White Solid
• InChI: InChI=1S/C22H27ClO3/c1-11(24)22(26)7-5-14-12-9-18(23)17-10-19(25)13-8-16(13)21(17,3)15(12)4-6-20(14,22)2/h9-10,12-16,26H,4-8H2,1-3H3/t12-,13+,14-,15-,16-,20-,21-,22-/m0/s1
• Code InChI: InChIKey=DUSHUSLJJMDGTE-ZJPMUUANSA-N
• SMILES: CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)[C@@H]5C[C@@H]5[C@]4(C)[C@H]3CC[C@@]21C