D-Cys(4)-Terlipressin Trifluoroacetic Acid Salt

CAS : 14636-12-5

Ref. TR-C997840

Informations sur le produit

• Nom: D-Cys(4)-Terlipressin Trifluoroacetic Acid Salt
• Synonymes: D-Cys(4)-Terlypressin Trifluoroacetic Acid Salt, N-(N-(N-Glycylglycyl)Glycyl)-8-L-Lysinevasopressin, (2S)-1-[(4S,7S,10S,13S,16S,19S)-19-[[2-[[2-[(2-Aminoacetyl)Amino]Acetyl]Amino]Acetyl]Amino]-13-Benzyl-10-(2-Carbamoylethyl)-7-(Carbamoylmethyl)-16-[(4-Hydroxyphenyl)Methyl]-6,9,12,15,18-Pentaoxo-1,2-Dithia-5,8,11,14,17-Pentazacycloicosane-4-Carbonyl]-N-[(1S)-5-Amino-1-(Carbamoylmethylcarbamoyl)Pentyl]Pyrrolidine-2-Carboxamide, (2S)-1-{[(4R,7S,10S,13S,16S,19R)-19-{[({[(aminoacetyl)amino]acetyl}amino)acetyl]amino}-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-N-{(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl}pyrrolidine-2-carboxamide (non-preferred name), Terlipressin Acetate, [N-α-Triglycyl-8-lysine]-vasopressin, 1-Triglycyl-8-lysine vasopressin, Glycylpressin, Glypressin, Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin, Nα-Glycyl-glycyl-glycyl-lysine-vasopressin, Nα-Glycylglycylglycyl-vasopressin, Nα-Gly-Gly-Gly-8-Lys-vasopressin, Remestyp, Terlipressina, Terlipressine, Triglycyl-8-lysine-vasopressin, Vasopressin, N-(glycylglycylglycyl)-8-L-lysine-, Vasopressin, N-[N-(N-glycylglycyl)glycyl]-8-L-lysine-

Description

Applications D-Cys(4)-Terlipressin is an impurity of Terlipressin (Diacetate Salt :T115800) which is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. Terlipressin is used norepinephrine-resistant septic shock and hepatorenal syndrome.
References Uriz, J. et al.: J. Heptol., 33, 43 (2000); O'Brien, A. et al.: Lancet, 359, 1209 (2002); Burroughs, A.K. et al.: Digestion, 59, 26 (1998); Villanueva, C. et al.: Am. J. Gastroenterol., 100, 624 (2005);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 1227.3711402
• Formule: C₅₂H₇₄N₁₆O₁₅S₂•x(C₂HF₃O₂)
• Couleur/Forme: Neat