Des(methylpiperazinyl) Imatinib Dimer Piperazinium Chloride (>80%)

CAS : 1821122-73-9

Ref. TR-D231455

Informations sur le produit

• Nom: Des(methylpiperazinyl) Imatinib Dimer Piperazinium Chloride (>80%)
• Synonymes: 1-Methyl-1,4-bis(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazin-1-ium Chloride

Description

Applications Des(methylpiperazinyl) Imatinib Dimer Piperazinium Chloride is an impurity of Imatinib Mesylate (G407000), a tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.
References Schindler, T., et al.: Science, 289, 1938 (2000); Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 923.5
• Formule: C₅₃H₅₁ClN₁₂O₂
• Degré de pureté: >80%
• Couleur/Forme: Neat
• SMILES: Cc1ccc(NC(=O)c2ccc(CN3CC[N+](C)(Cc4ccc(C(=O)Nc5ccc(C)c(Nc6nccc(-c7cccnc7)n6)c5)cc4)CC3)cc2)cc1Nc1nccc(-c2cccnc2)n1.[Cl-]