2-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate 1-Methanesulfonate

CAS : 122111-11-9

Ref. TR-D232790

Informations sur le produit

• Nom: 2-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate 1-Methanesulfonate
• Synonymes: [(2R,3R)-3-benzoyloxy-4,4-difluoro-5-methylsulfonyloxyoxolan-2-yl]methyl benzoate, T8, D-erythro-pentofuranose, 2-deoxy-2,2-difluoro-, 3,5-dibenzoate 1-methanesulfonate, 2-Dexy-2,2-Difluoro-3,5-O-Dibenzoylribose Mesylate, 2-Deoxy-2,2-Difluoro-D-Erythro-Ribofuranose-3,5-Dibenzoate 1-Methanesulfonate, 2-Deoxy-2,2-Difluoro-D-Ribofuranose-3,5-Dibenzoate-1-Methanesulfonate, 2-Deoxy-2,2-difluoro-3,5-dibenzoyl-D-ribofuranose-1-methanesulfonate, 2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate-1-methanesulfonate, 4-amino-1-[(2S,4S,5S)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one, 2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanesulfonate(racemate), 2-Deoxy-2,2-Difluoro-D-Erythro-Pentofuranose-3,5-Dibenzoate-1-Methanesulfonate(T8), T8:2-deoxy-2,2-difluoro-D-ribofuranose-3,5-dibenzoate-1-methanesulfonate

Description

Applications Gemcitabine intermediate.
References Balzarini, J., et al.: Biochem. Pharmacol., 1988, 37, 2847 (1988), Hertel, L., et al.: Cancer Res., 50, 4417 (1990), Marquez, V., et al.: J. Med. Chem., 33, 978 (1990),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 456.41
• Formule: C₂₀H₁₈F₂O₈S
• Couleur/Forme: Off-White To Light Yellow
• InChI: InChI=1S/C20H18F2O8S/c1-31(25,26)30-19-20(21,22)16(29-18(24)14-10-6-3-7-11-14)15(28-19)12-27-17(23)13-8-4-2-5-9-13/h2-11,15-16,19H,12H2,1H3/t15-,16-,19?/m1/s1
• Code InChI: InChIKey=LIAQHZDWFACWFK-QNRNLVPOSA-N
• SMILES: CS(=O)(=O)OC1O[C@H](COC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)C1(F)F