Diethyl 2-(3-Methylbutylidene)malonate

CAS : 51615-30-6

Ref. TR-D244100

Informations sur le produit

• Nom: Diethyl 2-(3-Methylbutylidene)malonate
• Synonymes: Propanedioic acid, 2-(3-methylbutylidene)-, 1,3-diethyl ester, Malonic acid, isopentylidene-, diethyl ester (6CI,7CI), Propanedioic acid, (3-methylbutylidene)-, diethyl ester (9CI), 2-(3-Methylbutylidene)malonic acid diethyl ester, Diethyl 2-(3-methylbuty, 1,3-Diethyl 2-(3-methylbutylidene)propanedioate, Diethyl (3-methylbutylidene)malonate, Diethyl 2-(3-methylbutylidene)malonate, Malonic acid, isopentylidene-, diethyl ester, NSC 30048, Propanedioic Acid, 2-(3-Methylbutylidene)-, Diethyl Ester, Propanedioic acid, (3-methylbutylidene)-, diethyl ester, Propanedioic acid, 2-(3-methylbutylidene)-, 1,3-diethyl ester

Description

Applications Diethyl 2-(3-methylbutylidene)malonate used in the preparation of pregabalin (P704790) which is a GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.
References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993); Field, M.J., et al.: Pain, 80, 391 (1999); Satyanarayana Reddy et al., U.S. Pat. Appl. Publ. (2010);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 228.285
• Formule: C₁₂H₂₀O₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C12H20O4/c1-5-15-11(13)10(8-7-9(3)4)12(14)16-6-2/h8-9H,5-7H2,1-4H3
• Code InChI: InChIKey=WSMCGEUISONHKL-UHFFFAOYSA-N
• SMILES: CCOC(=O)C(=CCC(C)C)C(=O)OCC