(-)-2'-Deoxy-3'-oxa-4'-thiocytidine (Apricitabine)

CAS : 160707-69-7

Ref. TR-D245513

Informations sur le produit

• Nom: (-)-2'-Deoxy-3'-oxa-4'-thiocytidine (Apricitabine)
• Synonymes: 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-, (2R-cis)-, 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv., 4- Amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-2(1H)-pyrimidinone, (-)-2'-Deoxy-3'-oxa-4'-thiocytidine, (-)-BCH 10652, AVX 754, Apricitabine, BCH 10618, SPD 754, (-)-2′-Deoxy-3′-oxa-4′-thiocytidine, (-)-Bch 10652, 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv., 2(1H)-Pyrimidinone, 4-amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-, 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-, (2R-cis)-, 4-Amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-2(1H)-pyrimidinone, Avx 754, Bch 10618, Spd 754

Description

Applications (-)-2'-Deoxy-3'-oxa-4'-thiocytidine (Apricitabine) is a drug that is used in the treatment of HIV aids. It as also been shown to be useful against lamivudine and zidovudine resistant virus strains
References Sebastian M., et al.: Org. Proc. Res. & Dev., 265, 763-773 (2011) Ghosh, R., et al.: Expert Opin. Pharmacother., 12, 31-46 (2011)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 229.25
• Formule: C₈H₁₁N₃O₃S
• Couleur/Forme: Neat
• InChI: InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-14-7(3-12)15-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7-/m1/s1
• Code InChI: InChIKey=RYMCFYKJDVMSIR-RNFRBKRXSA-N
• SMILES: Nc1ccn([C@H]2CO[C@@H](CO)S2)c(=O)n1