4-Descarboxamido Rufinamide 4-Methyl Ester

CAS : 217448-86-7

Ref. TR-D289555

Informations sur le produit

• Nom: 4-Descarboxamido Rufinamide 4-Methyl Ester
• Synonymes: Rufinamide Related Compound B,Methyl 1-(2,6-Difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate, Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate, Methyl 1-[(2,6-difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxylate, 1H-1,2,3-Triazole-4-carboxylic acid, 1-[(2,6-difluorophenyl)methyl]-, methyl ester, 1-(2,6-Difluorobenzyl)-1,2,3-triazole-4-carboxylic acid methyl ester, 1-(2,6-Difluorobenzyl)-1H-1,2,3-triazole-4-carboxylic acid methyl ester

Description

Applications 4-Descarboxamido Rufinamide 4-Methyl Ester is an impurity in the synthesis of Rufinamide (R701550), an antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.
References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 253.20
• Formule: C₁₁H₉F₂N₃O₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C11H9F2N3O2/c1-18-11(17)10-6-16(15-14-10)5-7-8(12)3-2-4-9(7)13/h2-4,6H,5H2,1H3
• Code InChI: InChIKey=SNCTXZHYCAQLHT-TZYZBQQFSA-N
• SMILES: C=C(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=CC=C4C(C)(C)[C@@H](O)CC[C@]4(C)C3CC[C@@]21C