21-Deschloro Clobetasol 17-Propionate

CAS : 4351-48-8

Ref. TR-D289573

Informations sur le produit

• Nom: 21-Deschloro Clobetasol 17-Propionate
• Synonymes: Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (11ß,16ß)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11ß,17-dihydroxy-16ß-methyl-, 17-propionate (7CI,8CI), (11ß,16ß)-9-Fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione, 21-Deoxybetamethasone 17-propionate, 9-Fluoro-11ß-hydroxy-16ß-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate, AH 5240, GR2/443, CCI 2212, Ph Eur Clobetasol Propionate Impurity H, CCI18747, CCI6990, CCI1822, 21-desoxybetamethasone-17-propionate, 16-ene, Ethylenic acid, USP Clobetasol propionate Related Compound A, (11Beta,16Beta)-9-Fluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Propanoate, (11β,16β)-9-Fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione, 9-Fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate, Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (11β,16β)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17-dihydroxy-16β-methyl-, 17-propionate

Description

Impurity Clobetasol Propionate EP Impurity H
Applications 21-Deschloro Clobetasol 17-Propionate possesses vasoconstrictor activity. Also, it is derived from Betamethasone 17-Propionate 21-Mesylate (Clobetasol Propionate EP Impurity), which is the 21-mesylate analogue of Betamethasone 17-Acetate (B327015) with anti-inflammatory activity.
References Busse, M. J., et al.: Br. J. Dermatol., 81, 103-111 (1969); Mitsukuchi, M. et al.: Chem. Pharm. Bull., 37, 3286 (1989);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 432.52
• Formule: C₂₅H₃₃FO₅
• Couleur/Forme: Neat
• InChI: InChI=1S/C25H33FO5/c1-6-21(30)31-25(15(3)27)14(2)11-19-18-8-7-16-12-17(28)9-10-22(16,4)24(18,26)20(29)13-23(19,25)5/h9-10,12,14,18-20,29H,6-8,11,13H2,1-5H3/t14-,18-,19-,20-,22-,23-,24-,25-/m0/s1
• Code InChI: InChIKey=ZAQGQQMIBBCIRM-RDEWRQEPSA-N
• SMILES: CCC(=O)O[C@]1(C(C)=O)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C