Desloratadine-d5 Hydrochloride

CAS : 432543-89-0

Ref. TR-D290307

Informations sur le produit

• Nom: Desloratadine-d5 Hydrochloride
• Synonymes: 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-d5 Hydrochloride, Aerius-d5 Hydrochloride, Allex-d5 Hydrochloride, Azomyr-d5 Hydrochloride, Clarinex-d5 Hydrochloride, Descarboethoxyloratadine-d5 Hydrochloride, NSC 675447-d5 Hydrochloride, Neoclarityn-d5 Hydrochloride, Opulis-d5 Hydrochloride, Sch 34117-d5 Hydrochloride

Description

Applications Desloratadine-d5 Hydrochloride is the labeled salt analogue of Desloratadine (D290250), a nonsedating-type histamine H1-receptor antagonist. An active metabolite of Loratadine. Also inhibits generation and release of inflammatory mediators from basophils and mast cells.
References Kreutner, W., et al.: Arzneimittel-Forsch., 50, 345 (2000); Salmun, L.M., et al.: Clin. Ther., 22, 613 (2000); Agrawal, D.K., et al.: Expert Opin. Invest. Drugs, 10, 547 (2001)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 352.31
• Formule: C₁₉H₁₅D₅Cl₂N₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C19H19ClN2.ClH/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13;/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2;1H/i1D,2D,3D2,9D
• Code InChI: InChIKey=XJJLVGAIFJSMSJ-XEUYGSPTSA-N
• SMILES: Cl.[2H]c1nc2c(c([2H])c1[2H])C([2H])([2H])Cc1cc(Cl)ccc1C2=C1CCNCC1