O-Desmethyl Midostaurin-13C6

CAS : 740816-86-8

Ref. TR-D291402

Informations sur le produit

• Nom: O-Desmethyl Midostaurin-13C6
• Synonymes: N-[(9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl]-N-methylbenzamide-13C6, CGP 62221-13C6, O-Desmethyl-PKC 412-13C6
• CAS: 740816-86-8

Description

Applications O-Desmethyl Midostaurin-13C6 is the labelled analogue of O-Desmethyl Midostaurin (D291400), a metabolite of Midostaurin (M343760), a compound shown to possess antiproliferative characteristics via inhibition of protein kinase C, kinase insert domain receptor, and c-kit.
References Tahtouh, T., et al.: J. Med. Chem., 55, 9312 (2012); Pedeboscq, S., et al.: PLoS. One., 7, 36811 (2012);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 562.57
• Formule: C₂₈₁₃C₆H₂₈N₄O₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C34H28N4O4/c1-34-31(39)24(36(2)33(41)18-10-4-3-5-11-18)16-25(42-34)37-22-14-8-6-12-19(22)27-28-21(17-35-32(28)40)26-20-13-7-9-15-23(20)38(34)30(26)29(27)37/h3-15,24-25,31,39H,16-17H2,1-2H3,(H,35,40)/t24-,25-,31-,34+/m1/s1/i3+1,4+1,5+1,10+1,11+1,18+1
• Code InChI: InChIKey=PXOCRDZEEXVZQC-ACPIPROWSA-N
• SMILES: CN(C(=O)[13c]1[13cH][13cH][13cH][13cH][13cH]1)[C@@H]1C[C@H]2O[C@@](C)([C@@H]1O)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4