N-Desmethyl Loperamide

CAS : 66164-07-6

Ref. TR-D291840

Informations sur le produit

• Nom: N-Desmethyl Loperamide
• Synonymes: 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N-methyl-α,α-diphenyl-, 4-(4-Chlorophenyl)-4-hydroxy-N-methyl-α,α-diphenyl-1-piperidinebutanamide, Desmethylloperamide, R 20905, N-Demethylloperamide
• Marque: TRC
• Description: Applications A metabolite of Loperamide; a new and improved PET radiotracer for imaging P-gp function. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Rahman, A., et al.: Cancer Res., 54, 5543 (1994), Sai, Y., et al.: Xenobiotica, 30, 327 (2000), Eneroth, A., et al.: Eur. J. Pharm. Sci., 12, 205 (2001), Kim, K., et al.: Drug Metab. Dispos., 31, 1090 (2003), Kannan et al. Drug Metab. Dispos., 38, 917 (2010)

Propriétés chimiques

• Masse moléculaire: 463.01
• Formule: C₂₈H₃₁ClN₂O₂
• Couleur/Forme: White To Light Beige
• InChI: InChI=1S/C28H31ClN2O2/c1-30-26(32)28(23-8-4-2-5-9-23,24-10-6-3-7-11-24)18-21-31-19-16-27(33,17-20-31)22-12-14-25(29)15-13-22/h2-15,33H,16-21H2,1H3,(H,30,32)
• Code InChI: InChIKey=ZMOPTLXEYOVARP-UHFFFAOYSA-N
• SMILES: CNC(=O)C(CCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1