4-Des((3-methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl)-4-hydroxy-N-(tert-butyl formate) Teneligliptin

CAS : 401564-34-9

Ref. TR-D293875

Informations sur le produit

• Nom: 4-Des((3-methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl)-4-hydroxy-N-(tert-butyl formate) Teneligliptin
• Synonymes: tert-butyl (2S,4S)-4-hydroxy-2-(1,3-thiazolidine-3-carbonyl)pyrrolidine-1-carboxylate

Description

Applications 4-Des((3-methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl)-4-hydroxy-N-(tert-butyl formate) Teneligliptin is a possible impurity of Teneligliptin (T018295), a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used to treat type 2 diabetes. It is eliminated via excretion, and has a half-life of 24.2 hours in the human body.
References Goda, M. & Kadowaki, T.: Drugs Today, 49, 615 (2013); Kishimoto, M.: Diabetes Metab. Syndr. Obes., 6, 187 (2012)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 302.39
• Formule: C₁₃H₂₂N₂O₄S
• Couleur/Forme: Neat
• InChI: InChI=1S/C13H22N2O4S/c1-13(2,3)19-12(18)15-7-9(16)6-10(15)11(17)14-4-5-20-8-14/h9-10,16H,4-8H2,1-3H3/t9-,10-/m0/s1
• Code InChI: InChIKey=CABJFRFFUZMDSS-UWVGGRQHSA-N
• SMILES: CC(C)(C)OC(=O)N1C[C@@H](O)C[C@H]1C(=O)N1CCSC1