N-Despropargyl N-(2-Chloroallyl) Rasagiline

CAS : 1175018-73-1

Ref. TR-D297635

Informations sur le produit

• Nom: N-Despropargyl N-(2-Chloroallyl) Rasagiline
• Synonymes: (1R)-N-(2-Chloro-2-propen-1-yl)-2,3-dihydro-1H-inden-1-amine

Description

Applications N-Despropargyl N-(2-Chloroallyl) Rasagiline is used in the preparation of Rasagiline mesylate and chloro derivative impurities. Also, a derivative compound of Rasagiline mesylate (R126000) that functions an irreversible MAO-B inhibitor and also as an antiparkinsonian agent.
References Sterling, J., et al.: U.S. (2009), US 7572834 B1 20090811; Rabey, J. M., et al.: Clin. Neuropharmacol., 23, 324 (2000), Glezer, S., et al.: Eur. J. Pharmacol., 472, 173 (2003), Youdim, M.B.H., et al.: Biochem. Pharmacol., 66, 1635 (2003), Chen, J .J., et al.: J. Clin. Pharmacol., 45, 878 (2005),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 207.70
• Formule: C₁₂H₁₄ClN
• Couleur/Forme: Yellow To Light Yellow
• InChI: InChI=1S/C12H14ClN/c1-9(13)8-14-12-7-6-10-4-2-3-5-11(10)12/h2-5,12,14H,1,6-8H2/t12-/m1/s1
• Code InChI: InChIKey=VMSMHLATUDKJLI-GFCCVEGCSA-N
• SMILES: C=C(Cl)CN[C@@H]1CCc2ccccc21