6-des-flouro-Fluticasone Furoate

CAS : 398454-97-2

Ref. TR-D398450

Informations sur le produit

• Nom: 6-des-flouro-Fluticasone Furoate
• Synonymes: Androsta-1,4-diene-17-carbothioic acid, 9-fluoro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-3-oxo-, S-(fluoromethyl) ester, (11ß,16a,17a)- (9CI), 9-Fluoro-17ß-[[(fluoromethyl)sulfanyl]carbonyl]-11ß-hydroxy-16a-methyl-3-oxoandrosta-1,4-dien-17a-yl fu

Description

Applications De-fluoro Fluticasone Furoate is a Furoate Fluticasone Furoate(F599510) raw material impurity which is a synthetic corticosteroid derived from fluticasone for treatment of seasonal allergic rhinitis.
References DeWester, J., et al.: Allergy Asthma Proc., 24, 331 (2003), Hughes, S., et al.: Drug Metab. Dispos., 36, 2337 (2008), Meltzer, E., et al.: Clin. Drug Investig., 29, 79 (2009),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 520.585
• Formule: C₂₇H₃₀F₂O₆S
• Couleur/Forme: Neat
• InChI: InChI=1S/C27H30F2O6S/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,23(33)36-14-28)35-22(32)20-5-4-10-34-20/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3/t15-,18+,19+,21+,24+,25+,26+,27+/m1/s1
• Code InChI: InChIKey=ZCAATYUQFSQTKA-ZULDAHANSA-N
• SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c1ccco1)C(=O)SCF