3’,5’-Di-O-benzyl Entecavir-13C2,15N

CAS : 142217-81-0

Ref. TR-D417552

Informations sur le produit

• Nom: 3’,5’-Di-O-benzyl Entecavir-13C2,15N
• Synonymes: 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-6H-purin-6-one-13C2,15N, [1S-(1alpha,3alpha,4beta)]-2-Amino-1,9-dihydro-9-[2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-6H-purin-6-one-13C2,15N, (1S,3R,4S)-2-amino-9-[4-(benzyloxy)-3-(benzyloxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one, Entecavir intermediate N8, 10-Oxy Iminostilbene Carbonyl Chloride, Entecavir intermediate N-1, 2-amino-9-{(1S,3R,4S)-4-(benzyloxy)-3-[(benzyloxy)methyl]-2-methylidenecyclopentyl}-1,9-dihydro-6H-purin-6-one, 2-amino-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl)-9H-purin-6-ol, The intermediate of Entecavir hydrate, (1S,3R,4S)-2-amino-9-[4-(benzyloxy)-3-(benzyloxymethyl)- 2-methylidene-cyclopentyl]-6H-purin-6-one, 2-amino-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclophentyl)-1H-purin-6(9H)-one, Entecavir intermediate 8, Intermediate of Entecavir 4, 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-, 2-amino-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one, 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one(E8), Entecavir E8

Description

Applications 3’,5’-Di-O-benzyl Entecavir is an intermediate in the preparation of the hepatitis B antiviral agent, Entecavir (E558900).
References Li, R. et al.: Zhong. Yao., 6, 292 (2008); Bisacchi, G.S. et al.: Bioorg. Med. Chem. Lett., 7, 127 (1997)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 460.503
• Formule: C₂C₂₄H₂₇NN₄O₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C26H27N5O3/c1-17-20(15-33-13-18-8-4-2-5-9-18)22(34-14-19-10-6-3-7-11-19)12-21(17)31-16-28-23-24(31)29-26(27)30-25(23)32/h2-11,16,20-22H,1,12-15H2,(H3,27,29,30,32)/t20-,21-,22-/m0/s1/i24+1,25+1,28+1
• Code InChI: InChIKey=KROVOOOAPHSWCR-YBJWFLRNSA-N
• SMILES: C=C1[C@@H](n2c[15n]c3[13c](=O)[nH]c(N)n[13c]32)C[C@H](OCc2ccccc2)[C@H]1COCc1ccccc1