2-(Dibutylamino)-1-(2,7-dichloro-9H-fluoren-4-yl)ethanol

CAS : 69759-61-1

Ref. TR-D426750

Informations sur le produit

• Nom: 2-(Dibutylamino)-1-(2,7-dichloro-9H-fluoren-4-yl)ethanol
• Synonymes: 2,7-Dichloro-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol
• Marque: TRC

Description

Applications 2-(Dibutylamino)-1-(2,7-dichloror-9H-fluoren-4-yl)ethanol is an impurity formed during the synthesis of Lumefantrine (L474000), a fluorene (F462000) derivative belonging to the aryl amino alcohol class of anti-malarial drugs.
References Verbeken, M., et al.: Malaria. J., 10, 51 (2011); Kim, K.H., et al.: J. Med. Chem., 22, 366 (1979);

Propriétés chimiques

• Masse moléculaire: 406.39
• Formule: C₂₃H₂₉Cl₂NO
• Couleur/Forme: Neat
• InChI: InChI=1S/C23H29Cl2NO/c1-3-5-9-26(10-6-4-2)15-22(27)21-14-19(25)13-17-11-16-12-18(24)7-8-20(16)23(17)21/h7-8,12-14,22,27H,3-6,9-11,15H2,1-2H3
• Code InChI: InChIKey=DALUOHFKVYCDCW-UHFFFAOYSA-N
• SMILES: CCCCN(CCCC)CC(O)c1cc(Cl)cc2c1-c1ccc(Cl)cc1C2