cis-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol

CAS : 138090-06-9

Ref. TR-D445070

Informations sur le produit

• Nom: cis-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol
• Synonymes: (5R,11R)-rel-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol, 5,11-cis-Diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol, cis-THC
• Marque: TRC
• Description: Applications cis-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol is a fluorescent and selective ligand that can be used to investigate the interactions between ligand and receptor of estrogen receptors (ERs) (1,2,3). cis-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol is an ERα agonist and an ERβ antagonist.References (1) Sumbayev, V. V., et al.: Mol Cell Endocrinol 287, 30 (2008) (2) Rosado, J., et al.: Biochem. J., 350, 631 (2000) (3) Dobrydneva, Y., et al.: J. Cardiovasc. Pharmacol., 40, 399 (2002)

Propriétés chimiques

• Masse moléculaire: 320.42
• Formule: C₂₂H₂₄O₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C22H24O2/c1-3-13-9-15-11-17(23)6-8-20(15)22-14(4-2)10-16-12-18(24)5-7-19(16)21(13)22/h5-8,11-14,23-24H,3-4,9-10H2,1-2H3/t13-,14-/m1/s1
• Code InChI: InChIKey=MASYAWHPJCQLSW-ZIAGYGMSSA-N
• SMILES: CC[C@@H]1Cc2cc(O)ccc2C2=C1c1ccc(O)cc1C[C@H]2CC