Rel-(2R, 3S)-Alpha-(2,4-Difluorophenyl)-5-fluoro-Beta-methyl-Alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol

CAS : 182230-43-9

Ref. TR-D446315

Informations sur le produit

• Nom: Rel-(2R, 3S)-Alpha-(2,4-Difluorophenyl)-5-fluoro-Beta-methyl-Alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
• Synonymes: ((2RS,3RS)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol), (2R,3S/2S,3R)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol, 2-(2,4-Difluoro-phenyl)-3-(5-fluoro-pyrimidin-4-yl)-1-[1,2,4]triazol-1-yl-butan-2-ol, 2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol, 2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, 4-Pyrimidineethanol, α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-, Racemic Voriconazole, α-(2,4-Difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol

Description

Impurity Voriconazole USP Related Compound A
Applications (2RS,3RS)α-(2,4-Difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol (Voriconazole USP Related Compound A), is a derivative of Voriconazole (V760000), which is a triazole antifungal medication that is generally used to treat serious fungal infections.
References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 349.31
• Formule: C₁₆H₁₄F₃N₅O
• Couleur/Forme: White to Off-White Solid
• InChI: InChI=1S/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3
• SMILES: C[C@@H](c1ncncc1F)[C@](O)(Cn1cncn1)c1ccc(F)cc1F.C[C@H](C1=NC=NC=[C+]1F)C(O)(Cn1cncn1)c1ccc(F)cc1F