(6Alpha,11Beta,16Alpha)-6,9-Difluoro-11,21-dihydroxy-21-methoxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione

CAS : 62013-83-6

Ref. TR-D446840

Informations sur le produit

• Nom: (6Alpha,11Beta,16Alpha)-6,9-Difluoro-11,21-dihydroxy-21-methoxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
• Synonymes: Fluocinolone Acetonide 21-Methoxy
• Marque: TRC

Description

Applications (6α,11β,16α)-6,9-Difluoro-11,21-dihydroxy-21-methoxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione is an intermediate in the synthesis of Fluocinolone Acetonide-21-aldehyde (F455810), a derivative of Fluocinolone Acetonide (F455800), which is a Corticosteroid, used in dermatology to reduce skin inflammation and relieve itching.
References Sirinivasu, P., et al.: Am. J. Anal. Chem., 1, 113 (2010);

Propriétés chimiques

• Masse moléculaire: 482.51
• Formule: C₂₅H₃₂F₂O₇
• Couleur/Forme: Neat
• InChI: InChI=1S/C25H32F2O7/c1-21(2)33-18-10-13-14-9-16(26)15-8-12(28)6-7-22(15,3)24(14,27)17(29)11-23(13,4)25(18,34-21)19(30)20(31)32-5/h6-8,13-14,16-18,20,29,31H,9-11H2,1-5H3/t13-,14-,16-,17-,18+,20?,22-,23-,24-,25-/m0/s1
• Code InChI: InChIKey=UXVHXUWPMPKQEY-PYXMUXJLSA-N
• SMILES: COC(O)C(=O)[C@@]12OC(C)(C)OC1C[C@H]1[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]12C