N-Desmethoxypropyl Prucalopride

CAS : 137211-64-4

Ref. TR-D446943

Informations sur le produit

• Nom: N-Desmethoxypropyl Prucalopride
• Synonymes: 4-Amino-5-chloro-2,3-dihydro-N-4-piperidinyl-7-benzofurancarboxamide

Description

Applications N-Desmethoxypropyl Prucalopride is an impurity of Prucalopride (P838950), a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.
References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 132.201
• Formule: C₁₄H₁₈ClN₃O₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C14H18ClN3O2/c15-11-7-10(13-9(12(11)16)3-6-20-13)14(19)18-8-1-4-17-5-2-8/h7-8,17H,1-6,16H2,(H,18,19)
• Code InChI: InChIKey=XKPTXCDASJWOLK-UHFFFAOYSA-N
• SMILES: CCCOC(C)OCC