20-Dihydro-corticosterone 21-Carboxylic Acid

CAS : 75879-79-7

Ref. TR-D452405

Informations sur le produit

• Nom: 20-Dihydro-corticosterone 21-Carboxylic Acid
• Synonymes: Pregn-4-en-21-oic acid, 11,20-dihydroxy-3-oxo-, (11ß)-, (11ß)-11,20-Dihydroxy-3-oxopregn-4-en-21-oic acid, 11ß,20-Dihydroxy-3-oxopregn-4-en-21-oic acid, 20-Dihydrocorticosterone-21-carboxylic acid, 11,20-Dihydroxy-3-Oxo-4-Pregnen-21-Oic Acid

Description

Applications 20-Dihydro-corticosterone 21-Carboxylic Acid is a new class of corticosteroids synthesized on the basis of the antedrug concept, possess local anti-inflammatory activity without systemic toxicties. It is also a pheramone that triggers natural behaviour in the vomeronasal system of mice.
References Bonzo, J.A., et al.: Molec. Endocrionol., 24, 2343 (2010); Cho. J.Y., et al.: J. Lipid. Res.,51, 1063 (2010); Fu, X., et al.: Cell, 163, 313 (2015)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 362.46
• Formule: C₂₁H₃₀O₅
• Couleur/Forme: Neat
• InChI: InChI=1S/C21H30O5/c1-20-8-7-12(22)9-11(20)3-4-13-14-5-6-15(18(24)19(25)26)21(14,2)10-16(23)17(13)20/h9,13-18,23-24H,3-8,10H2,1-2H3,(H,25,26)/t13-,14-,15+,16-,17+,18?,20-,21-/m0/s1
• Code InChI: InChIKey=NCZRCNAAHNGILW-WVQAOHMYSA-N
• SMILES: C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(O)C(=O)O