(R)-(-)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate

CAS : 23788-74-1

Ref. TR-D464975

Informations sur le produit

• Nom: (R)-(-)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate
• Synonymes: (4R)-2,2-Dimethyl-1,3-dioxolane-4-methanol 4-methylbenzenesulfonate, (R)-2,2-Dimethyl-1,3-dioxolane-4-methanol 4-, D-alpha,beta-isopropylidene glycerol-gamma-tosylate, (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-ylmethyl p-toluenosulfate, (R)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate, [(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate, (R)-(-)-2,2-Dimethyl-1,3-Dioxolan-4-Ylmethyl P-Toluenesulfonate

Description

Applications (R)-(-)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate is a chiral building block. It is used to prepare the antifungal agent ketoconazole. It is also used to prepare acyclic Nucleotide Analogs Derived from 8-Azapurines with antiviral activities.
References Rotstein, D., et al.: J. Med. Chem., 35, 2818 (1992); Holy, A., et al.: J. Med. Chem., 39, 4073 (1996)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 286.34
• Formule: C₁₃H₁₈O₅S
• Couleur/Forme: Neat
• InChI: InChI=1S/C13H18O5S/c1-10-4-6-12(7-5-10)19(14,15)17-9-11-8-16-13(2,3)18-11/h4-7,11H,8-9H2,1-3H3/t11-/m1/s1