2,3-Dimethyl-6-amino-2H-indazole Hydrochloride

CAS : 635702-60-2

Ref. TR-D471045

Informations sur le produit

• Nom: 2,3-Dimethyl-6-amino-2H-indazole Hydrochloride
• Synonymes: 2H-Indazol-6-amine, 2,3-dimethyl-, hydrochloride (1:1), 2H-Indazol-6-amine, 2,3-dimethyl-, monohydrochloride (9CI), 2,3-dimethyl-2H-indazol-6-amine hydrochloride, 2,3-dimethyl-2H-indazol-6-amine HCl, 6-Amino-2,3-dimethyl-2H-indazole hydrochloride, 2,3-Dimethyl-2H-indazol-6-amine monohydrochloride, 2,3-Dimethyl-6-amino-2H-indazole hydrochloride

Description

Stability Hygroscopic
Applications 2,3-Dimethyl-6-amino-2H-indazole is an impurity in the synthesis of Pazopanib (P210925) hydrochloride, an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
References Liu, D. et al.: J. Pharm. Biomed. Anal., 50, 144 (2009); Olaussen, K., et al.: Oncogen., 28, 4249 (2009); Sleijfer, S., et al.: J. Clin. Oncol., 27, 3126 (2009); Chan, A., et al.: Drugs, 69, 167 (2009)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 197.66
• Formule: C₉H₁₁N₃·ClH
• Couleur/Forme: Neat
• InChI: InChI=1S/C9H11N3.ClH/c1-6-8-4-3-7(10)5-9(8)11-12(6)2, 1H, /h3-5H,10H2,1-2H3
• Code InChI: InChIKey=DYTQJZDNKWQSLS-UHFFFAOYSA-N
• SMILES: Cc1c2ccc(N)cc2nn1C.Cl