Dimethyl (2-Oxopropyl)phosphonate

CAS : 4202-14-6

Ref. TR-D476790

Informations sur le produit

• Nom: Dimethyl (2-Oxopropyl)phosphonate
• Synonymes: (2-Oxopropyl)phosphonic Acid Dimethyl Ester, (Dimethylphosphono)acetone, (2-Oxopropyl)phosphonic acid dimethyl ester, 1-Dimethoxyphosphorylpropan-2-one, Acetylmethylphosphonic acid dimethyl ester~Dimethyl acetonylphosphonate~Dimethyl (2-oxopropyl)phosphonate, Dimethyl 2-oxopropanephosphonate, Dimethyl 2-oxopropylphosphonate, Dimethyl P-(2-oxopropyl)phosphonate, Dimethyl acetonylphosphonate, Dimethyl acetylmethylphosphonate, Dimethyl β-keto-propylphosphonate, Phosphonic acid, (2-oxopropyl)-, dimethyl ester, Phosphonic acid, P-(2-oxopropyl)-, dimethyl ester, Phosphonic acid, acetonyl-, dimethyl ester

Description

Applications Dimethyl (2-Oxopropyl)phosphonate is a common chemical reagent used in the synthesis of pharmaceuticals. Used in the synthesis of phenyl-substituted prostaglandins used as selective antiglaucoma agents. Also used in the synthesis of dipeptidyl enoates as potent rhodesain inhibitors. Rhodesain is the cysteine protease of Trypanosoma brucei parasites which cause African sleeping sickness.
References Resul, B. et al.: J. Med. Chem., 36, 243 (1993); Ehmke, V. et al.: ChemMedChem., 8, 965 (2013);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 166.11
• Formule: C₅H₁₁O₄P
• Couleur/Forme: Neat
• InChI: InChI=1S/C5H11O4P/c1-5(6)4-10(7,8-2)9-3/h4H2,1-3H3