5,7-Dinitro-8-quinolinol

CAS : 1084-32-8

Ref. TR-D480280

Informations sur le produit

• Nom: 5,7-Dinitro-8-quinolinol
• Synonymes: 5,7-Bis(hydroxyl[oxido]amino)-8-hydroxyquinoline, 5,7-Dinitro-8-hydroxyquinoline, 5,7-Dinitrooxine, 8-Hydroxy-5,7-dinitroquinoline, NSC 57103, NSC 74940, 8-Quinolinol, 5,7-Dinitro-

Description

Applications 5,7-Dinitro-8-quinolinol is a useful synthetic intermediate. It has been reported that 5,7-dinitro-8-hydroxyquinoline derivatives exhibit higher antimycobacterial activity than ciprofloxacin (C482500) against M. abscessus and M. Smegmatis. In addition, 5,7-Dinitro-8-quinolinol has been employed to investigate structure-activity relationships of nitroxoline derivatives that may provide new insights on developing novel cathepsin B inhibitors.
References Cieslik, W., et al.: Med Chem. 11, 771 (2015); Sosic, I., et al.: J. Med. Chem. 56, 521 (2013)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 235.15
• Formule: C₉H₅N₃O₅
• Couleur/Forme: Neat
• SMILES: O=[N+]([O-])c1cc([N+](=O)[O-])c2cccnc2c1O