(4aS,4bS,10aR,10bS,11S,12aS)-1,11-Dihydroxy-1-(hydroxymethyl)-10a,12a-dimethyl-4,4a,4b,5,6,10a,10b,11,12,12a-decahydrochrysene-2,8(1H,3H)-dione
Ref. TR-D489803
5mg | Arrêté | ||
10mg | Arrêté | ||
25mg | Arrêté |
Informations sur le produit
Applications (4aS,4bS,10aR,10bS,11S,12aS)-1,11-Dihydroxy-1-(hydroxymethyl)-10a,12a-dimethyl-4,4a,4b,5,6,10a,10b,11,12,12a-decahydrochrysene-2,8(1H,3H)-dione is an intermediate in the synthesis of (11β)-11,17a-Dihydroxy-17a-[(phosphonooxy)methyl]-D-homoandrosta-1,4-diene-3,17-dione Ammonium Salt (D455580), which is a derivative of Prednisolone (P703740), a glucocorticosteroid that is used to treat patients with chronic obstructive pulmonary disease (COPD).
References Burge, P., et al.: Thorax, 58, 654 (2003); Mendenhall, C., et al.: New Engl. J. Med., 311, 1464 (1984)