Dipyrone

CAS : 68-89-3

Ref. TR-D492860

Informations sur le produit

• Nom: Dipyrone
• Synonymes: sodium;[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-methylamino]methanesulfonate, Algocalmin, Algopyrin, Amoloid HV, Amoloid LV, Anador, Analgin, Analgin DAB10, Analgine, Andolor, Arpf, Collatex A/RE, Collatex Arm Extra, CollatexA/RE Extra, Conmel, Diprofarn, Dipyrone,hydrate, Duckammon, E 403, Gifaril, Kimica Algin NH, Kimitsu Algin NH, Lisador, Manutex PC-MV, Metamizol, Metamizole, Metamizole Sodium, Metamizole sodium salt, Metapyrin, Methamizole sodium, Methampyrone, Methanesulfonic acid, (antipyrinylmethylamino)-, sodium salt, Methanesulfonic acid, 1-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt (1:1), Methanesulfonic acid, [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt, Methylmelubrin, Metilon, Narone, Natrium-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methansulfonat, Neo-melubrine, Noramidopyrine methanesulfonate sodium, Noramidopyrine methanesulfonate sodium salt, Noraminophenazone methanesulfonate sodium salt, Noraminophenazone sodium mesylate, Novalgetol, Novalgin, Novamidazophen, Novaminophenazone, Novaminsulfone, Novaminsulfone sodium, Novaminsulfonium, Novaminsulfonum, Noveltex, Optalgin, Pharmalgine, Protamon S, Pyralgine, Pyretin, Pyretin (pharmaceutical), Restriva, Sodium ((2,3-Dihydro-1,5-Dimethyl-3-Oxo-2-Phenyl-1H-Pyrazol-4-Yl)Methylamino)Methanesulfonate, Sodium (antipyrinylmethylamino)methanesulfonate, Sodium 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonate, Sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonate, Sodium metamizole, Sodium noramidopyrine methanesulfonate, Sodium novaminsulfonate, Sulpin, Sulpyrin, Sulpyrine, [(1,5-Dimethyl-3-Oxo-2-Phenyl-Pyrazolidin-4-Yl)-Methyl-Amino]Methylsulfonyloxy Sodium, [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate, [(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonic acid sodium salt, [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazole-4-yl)methylamino]methanesulfonate de sodium, [(2-fenil-2,3-dihidro-1,5-dimetil-3-oxo-1H-pirazol-4-il)metilamino]metanosulfonato de sodio, sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate, sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate hydrate (1:1:1)

Description

Applications Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models. Neuroprotective & Neuroresearch Product.
References Reith, J., et al.: Lancet, 347, 422 (1996), Grau, A., et al.: J. Neurol. Sci., 171, 115 (1999), Schwarz, S., et al.: Neurology, 2000, 54, 354 (2000), Greer, D., et al.: Stroke, 39, 3029 (2008),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 333.34
• Formule: C₁₃H₁₆N₃O₄S·Na
• Couleur/Forme: White
• InChI: InChI=1S/C13H17N3O4S.Na/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;/h4-8H,9H2,1-3H3,(H,18,19,20);/q;+1/p-1
• Code InChI: InChIKey=UTNDKPRCMJHBSS-UHFFFAOYSA-N
• SMILES: Cc1c(N(C)CS(=O)(=O)O)c(=O)n(-c2ccccc2)n1C.[H].[Na]