Dipyrone-d3

CAS : 68-89-3

Ref. TR-D492862

Informations sur le produit

• Nom: Dipyrone-d3
• Synonymes: 1-[(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonic Acid-d3 Sodium Salt, (Antipyrinylmethylamino)methanesulfonic Acid-d3 Sodium Salt, ARPF-d3, Algocalmin-d3, Algopyrin-d3, Anador-d3, Analgin-d3, Analgine-d3, Andolor-d3, Conmel-d3, Diprofarn-d3, Gifaril-d3, Lisador-d3, Metamizol-d3, Metamizole-d3, Metamizole Sodium-d3, Metamizole Sodium Salt-d3, Metapyrin-d3, Methamizole-d3 Sodium, Methampyrone-d3, Methylmelubrin-d3, Metilon-d3, Narone-d3, Sulpin-d3, Sulpyrin-d3
• Marque: TRC
• Description: Stability HygroscopicApplications Labelled Dipyrone. Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models.References Reith, J. et al.: Lancet, 347, 422 (1996); Grau, A. et al.: J. Neurol. Sci., 171, 115 (1999); Schwarz, S. et al.: Neurology, 2000, 54, 354 (2000); Greer, D. et al.: Stroke, 39, 3029 (2008)

Propriétés chimiques

• Masse moléculaire: 336.36
• Formule: C₁₃H₁₃D₃N₃NaO₄S
• Couleur/Forme: Off-White
• InChI: InChI=1S/C13H17N3O4S.Na/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;/h4-8H,9H2,1-3H3,(H,18,19,20);/q;+1/p-1/i2D3
• Code InChI: InChIKey=DJGAAPFSPWAYTJ-MUTAZJQDSA-M
• SMILES: [2H]C([2H])([2H])N(CS(=O)(=O)O[Na])c1c(C)n(C)n(-c2ccccc2)c1=O