Di-2-thienylglycolic Acid

CAS : 4746-63-8

Ref. TR-D493915

Informations sur le produit

• Nom: Di-2-thienylglycolic Acid
• Synonymes: Glycolic acid, di-2-thienyl- (7CI,8CI), (Hydroxy)(di-2-thienyl)acetic acid, 2-Hydroxy-2,2-di(2-thienyl)acetic acid, alpha,alpha-Di(2-thienyl)glycolic acid, Tiotropium Bromide Monohydrate Imp A (EP), 2-Thiopheneacetic Acid, Alpha-Hydroxy-Alpha-2-Thienyl-, Hydroxy(di-2-thienyl)acetic acid

Description

Impurity Tiotropium Bromide EP Impurity A
Applications Di-2-thienylglycolic Acid is an analog of Methyl Di(2-thienylglycolate) (M303765), an intermediate in the production of Tiotropium Bromide (T444850), a long-acting bronchodilator.
References Prat, M., et al.: J. Med. Chem., 52, 5076 (2009); Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 240.30
• Formule: C₁₀H₈O₃S₂
• Couleur/Forme: Light Grey To Black
• InChI: InChI=1S/C10H8O3S2/c11-9(12)10(13,7-3-1-5-14-7)8-4-2-6-15-8/h1-6,13H,(H,11,12)
• Code InChI: InChIKey=FVEJUHUCFCAYRP-UHFFFAOYSA-N
• SMILES: O=C(O)C(O)(c1cccs1)c1cccs1