Docetaxal 2’-tert-Butyldimethylsilyl Ether

CAS : 1144034-14-9

Ref. TR-D525545

Informations sur le produit

• Nom: Docetaxal 2’-tert-Butyldimethylsilyl Ether
• Synonymes: (αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester
• Marque: TRC
• Description: Applications Docetaxal 2’-tert-Butyldimethylsilyl Ether is an intermediate in the synthesis of Docetaxal (D494565), an impurity of the semisynthetic derivative of Paclitaxel (P132500).References Naverez, D. M., et al: J. Am. Chem. Soc., 131, 5994 (2009)

Propriétés chimiques

• Masse moléculaire: 964.18
• Formule: C₅₁H₆₉NO₁₅Si
• Couleur/Forme: Neat
• InChI: InChI=1S/C51H69NO15Si/c1-28-33(63-44(58)39(67-68(13,14)47(7,8)9)37(31-21-17-15-18-22-31)52-45(59)66-46(4,5)6)26-51(60)42(64-43(57)32-23-19-16-20-24-32)40-49(12,34(55)25-35-50(40,27-61-35)65-30(3)54)41(56)38(62-29(2)53)36(28)48(51,10)11/h15-24,33-35,37-40,42,55,60H,25-27H2,1-14H3,(H,52,59)/t33-,34-,35+,37-,38+,39+,40-,42-,49+,50-,51+/m0/s1