2,5-Ethyl Acetate Febuxostat

CAS : 1643131-93-4

Ref. TR-E164310

Informations sur le produit

• Nom: 2,5-Ethyl Acetate Febuxostat
• Synonymes: Febuxostat Impurity, Febuxostat DEE Impurity, Ethyl 2-(3-(Ethoxycarbonyl)-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate, 2-[3-(Ethoxycarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid Ethyl Ester

Description

Applications Febuxostat (F229000) is the parent compound for 2,5-Ethyl Acetate Febuxostat. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 391.48
• Formule: C₂₀H₂₅NO₅S
• Couleur/Forme: Neat
• InChI: InChI=1S/C20H25NO5S/c1-6-24-19(22)15-10-14(8-9-16(15)26-11-12(3)4)18-21-13(5)17(27-18)20(23)25-7-2/h8-10,12H,6-7,11H2,1-5H3
• Code InChI: InChIKey=JSKGRJXDHUEKSV-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1cc(-c2nc(C)c(C(=O)OCC)s2)ccc1OCC(C)C