(2S,3R)-Efinaconazole

CAS : 164650-44-6

Ref. TR-E435085

Informations sur le produit

• Nom: (2S,3R)-Efinaconazole
• Synonymes: (2S,3R)-2-(2,4-Difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, (2R,3R)-2-(2,4-Difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(4H-1,3,4-triazol-4-yl)butan-2-ol, (R,R)-2-(2,4-Difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)-2-butanol, (αR,βR)-α-(2,4-Difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol, 1-Piperidineethanol, α-(2,4-difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-, (αR,βR)-, 1-Piperidineethanol, α-(2,4-difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-, [R-(R*,R*)]-, Jublia, KP 103 (pharmaceutical), Kp-103

Description

Applications (2S,3R)-Efinaconazole is the 2S,3R-enantiomer of Efinaconazole (E435070); a topical antifungal for onychomycosis.
References Sugiura, K., et. al.: Antimicrob. Agents CH., 58, 3837 (2014)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 348.39
• Formule: C₁₈H₂₂F₂N₄O
• Couleur/Forme: Neat
• InChI: InChI=1S/C18H22F2N4O/c1-13-5-7-23(8-6-13)14(2)18(25,10-24-12-21-11-22-24)16-4-3-15(19)9-17(16)20/h3-4,9,11-12,14,25H,1,5-8,10H2,2H3/t14?,18-/m0/s1
• Code InChI: InChIKey=NFEZZTICAUWDHU-IBYPIGCZSA-N
• SMILES: C=C1CCN(C(C)[C@@](O)(Cn2cncn2)c2ccc(F)cc2F)CC1