Eflornithine Hydrochloride Monohydrate

CAS : 96020-91-6

Ref. TR-E436000

Informations sur le produit

• Nom: Eflornithine Hydrochloride Monohydrate
• Synonymes: Ornithine, 2-(difluoromethyl)-, hydrochloride, hydrate (1:1:1), DL-Ornithine, 2-(difluoromethyl)-, monohydrochloride, monohydrate, Ornithine, 2-(difluoromethyl)-, monohydrochloride
• Marque: TRC

Description

Applications Irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism.
References Bacchi, C.J., et al.: Science, 210, 332 (1980); Haegele, K.D., et al.: Clin. Pharmacol. Ther., 30, 210 (1981); Meyskens, F.L., et al.: Clin. Cancer Res., 5, 945 (1999);

Propriétés chimiques

• Masse moléculaire: 236.64
• Formule: C₆H₁₂F₂N₂O₂·ClH·H₂O
• Couleur/Forme: Neat
• InChI: InChI=1S/C6H12F2N2O2.ClH.H2O/c7-4(8)6(10,5(11)12)2-1-3-9;;/h4H,1-3,9-10H2,(H,11,12);1H;1H2
• Code InChI: InChIKey=FJPAMFNRCFEGSD-UHFFFAOYSA-N
• SMILES: Cl.NCCCC(N)(C(=O)O)C(F)F.O