ent-Emtricitabine

CAS : 137530-41-7

Ref. TR-E525005

Informations sur le produit

• Nom: ent-Emtricitabine
• Synonymes: 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2S-cis)-, 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv., 4-Amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone, (+)-2'-Deoxy-3'-thia-5-fluorocytidine, (+)-FTC, (2'S,5'R)-Emtricitabine, 4-Amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one, (+)-2′-Deoxy-3′-thia-5-fluorocytidine, (+)-Ftc, 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv., 1-(2-(Hydroxymethyl)oxathiolan-5-yl)-5-fluorocytosine, 2',3',5-Ftc, 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, rel-, 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, cis-, 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2S-cis)-, 3'-Thia-2'.3'-dideoxy-5-fluorocytidine, 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one, 4-amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one, 5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine, 524W91, Bw 524W91, RCV, Racivir, 2',3'-Dideoxy-5-fluoro-3'-thiacytidine

Description

Stability Hygroscopic
Applications A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).
References Mellors, J., et al.: Science, 72, 1167 (1996), Reimann, K., et al.: J. Virol., 79, 8878 (2005), Rose, J., et al.: J. Biol. Chem., 280, 7413 (2005), Acierno, P., et al.: J. Immunol., 176, 5338 (2006),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 247.25
• Formule: C₈H₁₀FN₃O₃S
• Couleur/Forme: Neat
• InChI: InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m1/s1
• Code InChI: InChIKey=XQSPYNMVSIKCOC-RITPCOANSA-N
• SMILES: Nc1nc(=O)n([C@H]2CS[C@@H](CO)O2)cc1F