(6Alpha,9Beta,11Beta,16Alpha)-9,11-Epoxy-6-fluoro-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione

CAS : 68352-03-4

Ref. TR-E589285

Informations sur le produit

• Nom: (6Alpha,9Beta,11Beta,16Alpha)-9,11-Epoxy-6-fluoro-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
• Synonymes: Pregna-1,4-diene-3,20-dione, 9,11-epoxy-6-fluoro-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6a,9ß,11ß,16a)-, (6a,9ß,11ß,16a)-9,11-Epoxy-6-fluoro-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione, 9,11ß-Epoxy-6a-fluoro-21-hydroxy-16a,17-(1-methylethylidenedioxy)-9ß-pregna-1,4-diene-3,20-dione, (4aS,6aS,6bS,10aS,10bS,12S)-12-fluoro-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-5a,6,6a,6b,9a,10,10a,10b,11,12-decahydronaphtho[2',1':4,5]oxireno[5,6]indeno[1,2-d][1,3]dioxol-2(4aH)-one, (6α,9β,11β,16α)-9,11-Epoxy-6-fluoro-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione, 9beta,11beta-Epoxy-6alpha-fluoro-21-hydroxy-16alpha,17-(isopropylidene)dioxypregna-1,4-diene-3,20-dione, Pregna-1,4-diene-3,20-dione, 9,11-epoxy-6-fluoro-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6α,9β,11β,16α)-

Description

Impurity Fluocinolone Acetonide EP Impurity E
Stability Hygroscopic
Applications (6α,9β,11β,16α)-9,11-Epoxy-6-fluoro-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione, can be used in the production of fluocinolone acetonide (F455800).
References Grinenko, G.S, Khimiko-Farmatsevticheskii Zhurnal, 12, 110 (1978), Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 432.48
• Formule: C₂₄H₂₉FO₆
• Couleur/Forme: Neat
• InChI: InChI=1S/C24H29FO6/c1-20(2)29-18-9-13-14-8-16(25)15-7-12(27)5-6-21(15,3)23(14)19(30-23)10-22(13,4)24(18,31-20)17(28)11-26/h5-7,13-14,16,18-19,26H,8-11H2,1-4H3/t13-,14-,16-,18+,19-,21-,22-,23+,24+/m0/s1
• Code InChI: InChIKey=BYWOITQBHUGMQO-CHWIRLIISA-N
• SMILES: CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]45O[C@H]5C[C@]3(C)[C@]2(C(=O)CO)O1