Ethyl Loflazepate

CAS : 29177-84-2

Ref. TR-E679525

Informations sur le produit

• Nom: Ethyl Loflazepate
• Synonymes: 1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-oxo-, ethyl ester, 1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-5-(o-fluorophenyl)-2,3-dihydro-2-oxo-, ethyl ester (8CI), CM 6912, Ethyl[7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-oxo-1H-1,4-benzodiazepine-3-carboxylate], Meilax, Victan, 1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-oxo-, ethyl ester, 1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-5-(o-fluorophenyl)-2,3-dihydro-2-oxo-, ethyl ester, Brn 0765264, Cm 6912, DEA No. 2758, Ethyl fluclozepate, Ethyl loflazepate, Ethyl loflazepate [INN:JAN], Ethylis loflazepas, Ethylis loflazepas [INN-Latin], Loflazepate d'ethyle, Loflazepate d'ethyle [INN-French], Loflazepato de etilo, Loflazepato de etilo [INN-Spanish], Loflazepic acid, ethyl ester, Unii-Vjb5Fw9W9J, ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepine-3-carboxylate

Description

Applications A new benzodiazepine derivative as a new anti-anxiety drug. Ethyl Loflazepate and its metabolite were compared with those of Diazepam (D416855), Nitrazepam (N490140) and Lorazepam (L469850). The anticonflict effect of Ethyl Loflazepate was slightly more potent than that of Diazepam and much more potent than that of Lorazepam. Controlled substance.
References Cano J.P., et al.: J. Chromatogr., 226, 413 (1981), Tanaka M., et al.: Clin. Neuropharmacology, (1985), 8, 271 (1985),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 360.77
• Formule: C₁₈H₁₄ClFN₂O₃
• Couleur/Forme: White
• InChI: InChI=1S/C18H14ClFN2O3/c1-2-25-18(24)16-17(23)21-14-8-7-10(19)9-12(14)15(22-16)11-5-3-4-6-13(11)20/h3-9,16H,2H2,1H3,(H,21,23)
• Code InChI: InChIKey=CUCHJCMWNFEYOM-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1N=C(c2ccccc2F)c2cc(Cl)ccc2NC1=O