Desmethyl-O-Benzyl Apixaban Carboxylate

CAS : 1620494-29-2

Ref. TR-E702870

Informations sur le produit

• Nom: Desmethyl-O-Benzyl Apixaban Carboxylate
• Synonymes: ethyl 7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-1-(4-phenylmethoxyphenyl)-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate

Description

Applications Apixaban(A726700) Impurity. Apixaben is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation. Apixaban Impurity.
References Luettgen, J.M., et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T., et al.: J. Thromb. Thrombol., 31, 310 (2011); Barrett, Y.C., et al.: Thromb. Haemos., 105, 181 (2011);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 564.631
• Formule: C₃₃H₃₂N₄O₅
• Couleur/Forme: Neat
• InChI: InChI=1S/C33H32N4O5/c1-2-41-33(40)30-28-19-21-36(25-13-11-24(12-14-25)35-20-7-6-10-29(35)38)32(39)31(28)37(34-30)26-15-17-27(18-16-26)42-22-23-8-4-3-5-9-23/h3-5,8-9,11-18H,2,6-7,10,19-22H2,1H3
• Code InChI: InChIKey=NQADJRHKQGNFII-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1nn(-c2ccc(OCc3ccccc3)cc2)c2c1CCN(c1ccc(N3CCCCC3=O)cc1)C2=O