17α-Estradiol

CAS : 57-91-0

Ref. TR-E887995

Informations sur le produit

• Nom: 17α-Estradiol
• Synonymes: 17alpha-Estradiol, 17-epi-Estradiol, Estra-1,3,5(10)-triene-3,17alpha-diol, Estradiol Hemihydrate Imp. B (EP), Ethinylestradiol Imp. L (EP), Estradiol Imp. B (EP), Ethinylestradiol Imp. D (EP), Estradiol Hemihydrate Impurity B, Estriol Impurity J, Ethinylestradiol Impurity L, Estradiol Impurity B, (17Alpha)-Estra-1,3,5(10)-Triene-3,17-Diol, (17α)-Estra-1,3,5(10)-triene-3,17-diol, (8Xi,13Xi,17Alpha)-Estra-1,3,5(10)-Triene-3,17-Diol, 1,3,5-Estratriene-3,17-Alpha-Diol, 1,3,5-Estratriene-3,17alpha-diol, 1,3,5-Estratriene-3,17α-diol, 13β-Methyl-1,3,5(10)-gonatriene-3,17α-diol, 17-Epiestradiol, 17A-estradiol, 17ALPHA-Estradiol, 17alpha-Oestradiol, 17α-Oestradiol, 3,17-Alpha-Dihydroxyoestra-1,3,5(10)-Triene, 3,17-Dihydroxyestratriene, 3,17alpha-Dihydroxyestra-1,3,5(10)-triene, 3,17alpha-Dihydroxyoestra-1,3,5(10)-triene, 3,17α-Dihydroxyestra-1,3,5(10)-triene, 3,17α-Dihydroxyoestra-1,3,5(10)-triene, 5(10)-Triene-3,17-Diol,(17-Alpha)-Estra-3, Alfatradiol, Alpha-Estradiol, Epiestradiol, Epiestrol, Estra-1,3,5(10)-Triene-3,17Α-Diol, Estra-1,3,5(10)-Trieno-3,17Α-Diol, Estra-1,3,5(10)-trien-3,17α-diol, Estra-1,3,5(10)-triene-3,17-diol, (17alpha)-, Estra-1,3,5(10)-triene-3,17-diol, (17α)-, Estradiol, 17alpha-, Migenix, Mito 4509, Nsc 20293, Oestra-1,3,5(10)-triene-3,17alpha-diol, Oestra-1,3,5(10)-triene-3,17α-diol, Oestradiol (E2), 17-Alpha-, Oestradiol (E2), 17-Beta, Oestradiol-17-Alpha, Oestradiol-17alpha

Description

Impurity Estradiol 17?-Hydroxy Impurity; Estradiol EP Impurity B; Ethinylestradiol EP Impurity L
Applications Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain(1,2). 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke(3).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.
References 1. Lievertz, R. et al.: J. Obstet. Gynecol. 1987 May;156(5):1289-932. Kuhnz, W. et al.: Arzneimittelforschung. 1993 Sep;43(9):966-73.3. Toran-Allerand, C. et al.: Endocrinology. 2005 Sep;146(9):3843-50.

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 272.38
• Formule: C₁₈H₂₄O₂
• Couleur/Forme: White
• InChI: InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1
• Code InChI: InChIKey=VOXZDWNPVJITMN-SFFUCWETSA-N
• SMILES: C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@H]2O