17α-Estradiol-16,16,17-d3

CAS : 79037-37-9

Ref. TR-E887997

Informations sur le produit

• Nom: 17α-Estradiol-16,16,17-d3
• Synonymes: (17α)-Estra-1,3,5(10)-triene-3,17-diol-d3, 1,3,5-Estratriene-3,17α-diol-d3, 13β-Methyl-1,3,5(10)-gonatriene-3,17α-diol-d3, 17-Epiestradiol-d3, 17α-Oestradiol-d3, 3,17-Dihydroxyestratriene-d3, 3,17α-Dihydroxyoestra-1,3,5(10)

Description

Applications Labelled Estradiol. Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke.
References Salole, E.G., Anal. Profiles Drug Subs., 15, 283 (1986), Lievertz, R.W., et al.: Am. J. Obstret. Gynecol., 156, 1289 (1987), Kuhnz, W., et al.: Arzneim.-Forsch., 43, 966 (1993),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 275.4
• Formule: C₁₈H₂₁D₃O₂
• Couleur/Forme: White To Off-White
• InChI: InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1/i7D2,17D
• Code InChI: InChIKey=VOXZDWNPVJITMN-JCNODAHJSA-N
• SMILES: [2H]C1([2H])C[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]2(C)[C@]1([2H])O