Ethyl 3-Aminocrotonate

CAS : 7318-00-5

Ref. TR-E898080

Informations sur le produit

• Nom: Ethyl 3-Aminocrotonate
• Synonymes: 3-Amino-2-butenoic Acid Ethyl Ester, beta-Aminocrotonic Acid Ethyl Ester, 3-Aminocrotonic Acid Ethyl Ester, Ethyl 3-Amino-2-butenoate, Ethyl beta-Amino-beta-methylacrylate, Ethyl beta-Aminocrotonate, NSC 1086, beta-Aminocrotonic Acid Ethyl Ester, 2-Butenoic acid, 3-amino-, ethyl ester, 3-Amino-2-Butenoic Acid Ethyl Ester, Beta-Aminocrotonic Acid Ethyl Ester, Crotonic Acid, 3-Amino-, Ethyl Ester, Crotonic acid, β-amino-, ethyl ester, Ethyl (2e)-3-Amino-2-Butenoate, Ethyl (2e)-3-Aminobut-2-Enoate, Ethyl 3-Amino-2-Butenoate, Ethyl 3-Aminobut-2-Enoate, Ethyl Aminocrotonate, Ethyl B-Iminobutyrate, Ethyl Beta-Aminocrotonate, Ethyl β-amino-β-methylacrylate, Ethyl β-aminocrotonate, ethyl (2Z)-3-aminobut-2-enoate, ethyl (3E)-3-iminobutanoate, Β-Aminocrotonic Acid, Ethyl Ester, Ethyl-3-aminocrotonate

Description

Applications Ethyl 3-Aminocrotonate is used as a reagent to synthesize Nitrendipine (N490150), a calcium channel antagonist that is used to treat patients with hypertension. Ethyl 3-Aminocrotonate is also used as a reagent to synthesize (S)-Felodipine (F232370), a calcium entry blocker that has antihypertensive properties.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bailey, D., et al.: Clin. Invest. Med., 12, 357 (1989); Bean, B.: Proc. Nat. Acad. Sci., 81, 6388 (1984); Kwon, K., et al.: Tetrahedron, 67, 10222 (2011); Leenen, F. & Holiwell, D.: Am. J. Cardio., 69, 639 (1992); Meyer, H., et al.: Arz. Forsch., 33, 1528 (1983); Stoepel, K., et al.: Arz. Forsch., 31, 2056 (1980)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 129.16
• Formule: C₆H₁₁NO₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C6H11NO2/c1-3-9-6(8)4-5(2)7/h4H,3,7H2,1-2H3/b5-4-
• Code InChI: InChIKey=YPMPTULBFPFSEQ-PLNGDYQASA-N
• SMILES: CCOC(=O)/C=C(/C)N