4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]benzenesulfonyl Chloride

CAS : 119043-16-2

Ref. TR-E917518

Informations sur le produit

• Nom: 4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]benzenesulfonyl Chloride
• Synonymes: 4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]-benzenesulfonyl Chloride, 4-[2-[(4-ethyl-3-methyl-5-oxo-2H-pyrrole-1-carbonyl)amino]ethyl]benzenesulfonyl chloride, Benzenesulfonyl chloride, 4-[2-[[(3-ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]-, Glmn-B, 4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]benzenesulfonyl chloride

Description

Applications 4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]benzenesulfonyl Chloride is an intermediate in the synthesis of 4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide (E925045), which is an intermediate for the preparation of Glimepiride. Glimepiride is a sulfonylurea hypoglycemic agent, used as an antidiabetic.
References Ratheiser, K., et al.: Arzneim.-Forsch., 43, 856, (1993)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 370.851
• Formule: C₁₆H₁₉ClN₂O₄S
• Couleur/Forme: Neat
• InChI: InChI=1S/C16H19ClN2O4S/c1-3-14-11(2)10-19(15(14)20)16(21)18-9-8-12-4-6-13(7-5-12)24(17,22)23/h4-7H,3,8-10H2,1-2H3,(H,18,21)
• Code InChI: InChIKey=KEFLFSMLSAEGQB-UHFFFAOYSA-N
• SMILES: CCC1=C(C)CN(C(=O)NCCc2ccc(S(=O)(=O)Cl)cc2)C1=O