FAICAR ~85%

CAS : 13018-54-7

Ref. TR-F101065

Informations sur le produit

• Nom: FAICAR ~85%
• Synonymes: 5-Formylamino-4-imidazolecarboxamide Ribonucleotide, 5-(Formylamino)-1-(5-O-phosphono-ß-D-ribofuranosyl)-1H-imidazole-4-carboxamide, 5-Formamido-1-ß-D-ribofuranosyl-,5'-(dihydrogen phosphate)-imidazole-4-carboxamide, 1H-Imidazole-4-carboxamide, 5-(formylamino)-1-(5-O-phosphono-beta-D-ribofuranosyl)-, 1H-Imidazole-4-carboxamide, 5-(formylamino)-1-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-, 5-(Formylamino)-1-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-1H-imidazole-4-carboxamide, 5-(formylamino)-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide, 5-Formylamino-4-imidazolecarboxamide ribonucleotide, Faicar, Imidazole-4-carboxamide, 5-formamido-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 5′-(dihydrogen phosphate)

Description

Applications FAICAR is the derivative of AICAR (A611700), which is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 366.22
• Formule: C₁₀H₁₅N₄O₉P
• Degré de pureté: ~85%
• Couleur/Forme: Off-White To Dark Brown
• InChI: InChI=1S/C10H15N4O9P/c11-8(18)5-9(13-3-15)14(2-12-5)10-7(17)6(16)4(23-10)1-22-24(19,20)21/h2-4,6-7,10,16-17H,1H2,(H2,11,18)(H,13,15)(H2,19,20,21)/t4-,6-,7-,10-/m1/s1
• Code InChI: InChIKey=ABCOOORLYAOBOZ-KQYNXXCUSA-N
• SMILES: NC(=O)c1ncn([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c1NC=O