Fangchinoline

CAS : 33889-68-8

Ref. TR-F102365

Informations sur le produit

• Nom: Fangchinoline
• Synonymes: (4aS,16aR)3,4,4a,5,16a,17,18,19-Octahydro-12,21,26-trimethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-22-ol, 6,6',12-Trimethoxy-2,2'-dimethyl-berbaman-7-ol, Thalrugosine, (+)-Thalrugosine, [4aS-(4aR*,16aS*)]-3,4,4a,5,16a,17,18,19-Octahydro-12,21,26-trimethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-22-ol, Isofangchinoline, NSC 277171, Thaligine, d-Isofangchinoline, (+)-Hanfangichin B, 6,6',12-Trimethoxy-2,2'-Dimethylberbaman-7-Ol, (1beta)-6,6',12-Trimethoxy-2,2'-dimethylberbaman-7-ol

Description

Applications Fangchinoline is an isolate from Stephania Tetrandra that shows anti-cancer activity. It inhibits breast adenocarcinoma proliferation through apoptosis induction. In addition, it has been shown to inhibit HIV-Type 1 replication.
References Xing, Z. et al.: Chem. Pharm. Bull., 59, 1476 (2011); Wan, Z. et al.: PLoS One. 7, e39225 (2012);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 608.72
• Formule: C₃₇H₄₀N₂O₆
• Couleur/Forme: Neat
• InChI: InChI=1S/C37H40N2O6/c1-38-14-12-24-19-31(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-32-18-23(8-11-30(32)41-3)17-29-35-25(13-15-39(29)2)20-34(43-5)36(40)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1-5H3/t28-,29+/m0/s1
• Code InChI: InChIKey=IIQSJHUEZBTSAT-URLMMPGGSA-N
• SMILES: COc1ccc2cc1Oc1ccc(cc1)C[C@H]1c3cc(c(OC)cc3CCN1C)Oc1c(O)c(OC)cc3c1[C@@H](C2)N(C)CC3