Fexofenadine

CAS : 83799-24-0

Ref. TR-F322470

Informations sur le produit

• Nom: Fexofenadine
• Synonymes: Benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-a,a-dimethyl-, 4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-a,a-dimethylbenzeneacetic acid, 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-a,a-dimethylphenylacetic acid, Carboxyterfenadine, Fexet, MDL 16455, Telfast 120, Terfenadine acid metabolite, Terfenadine carboxylate, 2-(4-[1-Hydroxy-4-[4-(hydroxy-diphenyl-methyl)-piperidin-1-yl]-butyl]-phenyl)-2-methyl-propionic acid, 2-(4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl]phenyl)-2-methylpropanoic acid, 2-[4-(1-Hydroxy-4-{4-[Hydroxy(Diphenyl)Methyl]Piperidin-1-Yl}Butyl)Phenyl]-2-Methylpropanoic Acid, 4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethylbenzeneacetic acid, 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylphenylacetic acid, Benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, Mdl 16455, Terfenidine Carboxylate

Description

Applications The active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist.
References Garteiz, D.A., et al.: Arzneim.-Forsch., 32, 1185 (1982), Rampe, D., et al.: Mol. Pharmacol., 44, 1240 (1993), Obradovic, T., et al.: Pharm. Res., 24, 318 (2007),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 501.66
• Formule: C₃₂H₃₉NO₄
• Couleur/Forme: Off-White
• InChI: InChI=1S/C32H39NO4/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36)
• Code InChI: InChIKey=RWTNPBWLLIMQHL-UHFFFAOYSA-N
• SMILES: CC(C)(C(=O)O)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1