Flumethasone 21-Pivalate

CAS : 2002-29-1

Ref. TR-F455015

Informations sur le produit

• Nom: Flumethasone 21-Pivalate
• Synonymes: 6a,9-Difluoro-11ß,17-dihydroxy-16a-methyl-3,20-dioxopregna-1,4-dien-21-yl 2,2-dimethylpropanoate, Pregna-1,4-diene-3,20-dione, 21-(2,2-dimethyl-1-oxopropoxy)-6,9-difluoro-11,17-dihydroxy-16-methyl-, (6a,11ß,16a)-, Pregna-1,4-diene-3,20-dione, 6a,9-difluoro-11ß,17,21-trihydroxy-16a-methyl-, 21-pivalate (7CI,8CI), Pivalic acid, 21-ester with 6a,9-difluoro-11ß,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione (8CI), 6a,9a-Difluoro-11ß,17a,21-trihydroxy-16a-methyl-1,4-pregnadiene-3,20-dione 21-pivalate, 6a,9a-Difluoro-16a-methylprednisolone 21-pivalate, Flumetasone 21-pivalate, Flumetasone pivalate, Flumethasone pivalate, Locacorten, Locorten, Lorinden, Losalen, NSC 107680, (6α,11β,16α)-21-(2,2-Dimethyl-1-oxopropoxy)-6,9-difluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, 21-Pivalate De Flumetasone, 21-Pivalato De Flumetasona, 6α,9α-Difluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-pivalate, 6α,9α-Difluoro-16α-methylprednisolone 21-pivalate, Flumetason-21-pivalat, Flumetasone 21-Pivalate, Flumethasone 21-pivalate, Nsc 107680, Pivalic acid, 21-ester with 6α,9-difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione, Pregna-1,4-diene-3,20-dione, 21-(2,2-dimethyl-1-oxopropoxy)-6,9-difluoro-11,17-dihydroxy-16-methyl-,, Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,17,21-trihydroxy-16α-methyl-, 21-pivalate, Pregna-1,4-diene-3,20-dione, 21-(2,2-dimethyl-1-oxopropoxy)-6,9-difluoro-11,17-dihydroxy-16-methyl-, (6α,11β,16α)-

Description

Applications An anti-inflammatory anti-itching corticosteroid found in topical creams.
References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Hoeller, S., et al.: J. Pharm. Sci., 98, 2686 (2009), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 494.57
• Formule: C₂₇H₃₆F₂O₆
• Couleur/Forme: Neat
• InChI: InChI=1S/C27H36F2O6/c1-14-9-16-17-11-19(28)18-10-15(30)7-8-24(18,5)26(17,29)20(31)12-25(16,6)27(14,34)21(32)13-35-22(33)23(2,3)4/h7-8,10,14,16-17,19-20,31,34H,9,11-13H2,1-6H3/t14-,16+,17+,19+,20+,24+,25+,26+,27+/m1/s1
• Code InChI: InChIKey=JWRMHDSINXPDHB-OJAGFMMFSA-N
• SMILES: C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(=O)C(C)(C)C